What makes a trait autosomal

Diagnosis and Staging. Questions to Ask about Your Diagnosis. Types of Cancer Treatment. Side Effects of Cancer Treatment. Clinical Trials Information. A to Z List of Cancer Drugs. Questions to Ask about Your Treatment. Feelings and Cancer. Adjusting to Cancer. Day-to-Day Life. Support for Caregivers.

Questions to Ask About Cancer. Choices for Care. Talking about Your Advanced Cancer. Planning for Advanced Cancer. Advanced Cancer and Caregivers. Questions to Ask about Advanced Cancer. Managing Cancer Care. Finding Health Care Services.

Advance Directives. Using Trusted Resources. Coronavirus Information for Patients. Clinical Trials during Coronavirus.

Adolescents and Young Adults with Cancer. Emotional Support for Young People with Cancer. Cancers by Body Location. Late Effects of Childhood Cancer Treatment.

Pediatric Supportive Care. Rare Cancers of Childhood Treatment. Childhood Cancer Genomics. Study Findings. Metastatic Cancer Research. Autosomal conditions occur in both men and women and are not related to whether a person is male or female.

In an autosomal recessive disorder, two changed copies of a gene are inherited—one from each of the parents—which causes the child to have the disorder. A carrier has only one changed copy of the gene. Although they have one copy of a gene that is changed, the partner copy of the gene is working correctly, so they do not develop the disorder.

When both parents are carriers for a recessive disorder, each child has a 1 in 4 25 percent chance of inheriting the two changed gene copies. There is a 1 in 2 50 percent chance that the child will inherit one changed copy and one normal copy of the gene, and therefore be an unaffected carrier just like the parent.

There is a 1 in 4 25 percent chance that the child will inherit both normal copies of a gene, and be unaffected and not a carrier. If only one parent is a carrier and the other is not, none of the children will have the condition. Mayo Clinic does not endorse any of the third party products and services advertised.

A single copy of these materials may be reprinted for noncommercial personal use only. This content does not have an English version. This content does not have an Arabic version. See more conditions. Autosomal dominant inheritance pattern. Products and services. Dominant inheritance means an abnormal gene from one parent can cause disease. This happens even when the matching gene from the other parent is normal.

The abnormal gene dominates. This disease can also occur as a new condition in a child when neither parent has the abnormal gene. This is true for each pregnancy. It means that each child's risk for the disease does not depend on whether their sibling has the disease.

If someone is diagnosed with an autosomal dominant disease, their parents should also be tested for the abnormal gene.